medullary Thyroid cancer

A neuroendocrine carcinoma that originates in the C-cells of the THYROID GLAND; about 10-20% of cases are familial. It occurs sporadically or is associated with MULTIPLE ENDOCRINE NEOPLASIA SYNDROMES. Germline and somatic mutations in RET and NTRK1 genes have been identified. OMIM: 155240

Also Known As:

Thyroid cancer, medullary; Medullary thyroid cancer (MTC); Thyroid carcinoma, medullary

Neoplasms: 1361496
- Neoplasms by Site: 4
  - Head and Neck Neoplasms: 18631
    - Thyroid Neoplasms: 18499
      - medullary Thyroid cancer: 986
  - Endocrine Gland Neoplasms: 135
    - Thyroid Neoplasms: 18499
      - medullary Thyroid cancer: 986
- Neoplasms by Histologic Type: 2
  - Germ Cell and Embryonal Neoplasms: 4514
    - Neuroectodermal Tumors: 216
      - Neuroendocrine Tumors: 6524
        Neuroendocrine Carcinoma: 1163
        medullary Thyroid cancer: 986
  - Glandular and Epithelial Neoplasms: 445
    - Carcinoma: 143226
      - Adenocarcinoma: 59622
        Neuroendocrine Carcinoma: 1163
        medullary Thyroid cancer: 986
  - Nerve Tissue Neoplasms: 1
    - Neuroectodermal Tumors: 216
      - Neuroendocrine Tumors: 6524
        Neuroendocrine Carcinoma: 1163
        medullary Thyroid cancer: 986
Endocrine System Diseases: 996
- Thyroid Diseases: 6248
  - Thyroid Neoplasms: 18499
    - medullary Thyroid cancer: 986
- Endocrine Gland Neoplasms: 135
  - Thyroid Neoplasms: 18499
    - medullary Thyroid cancer: 986

S Scherl Selected Research

S Scherl Research Topics

Disease

Drug/Important Bio-Agent (IBA)